Compositions containing .beta..sub.2 adrenergic agonists in combination with carbonates and carbamates of the formula ##STR00001## and in combination with related steroid carbonates and carbamates are disclosed. The compositions are useful for treating bronchospasm, for inducing bronchodilation and for treating rhinitis, asthma, and chronic obstructive pulmonary disease (COPD) and inflammatory diseases, particularly by inhalation.