An instruction buffer of the present invention includes a sequence of instructions arranged in an order determined beforehand, and a buffer including entries arranged in a preselected order for storing the sequence of instructions. Any one of the instructions stored in any one of the entries designated by a low entry number is prior, in order, to another instruction stored in another entry designated by a high entry number.

 
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> Pyrazolo[3,4-b]pyridin-6-ones as GSK-3 inhibitors

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