A bottom dispensing aerosol device is disclosed comprising an aerosol container with an aerosol valve located at a bottom portion of the aerosol container. A coupling mounts an undercap to the aerosol container with a top portion of the undercap being adjacent to a bottom portion of the aerosol container. A bottom portion of the undercap supports the aerosol container on a supporting surface in an inverted position. An actuator is provided for opening the aerosol valve for discharging the aerosol product from the aerosol container when the bottom portion of the undercap is supporting the aerosol container in the inverted position on a supporting surface.

 
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> Compounds and therapeutic uses thereof

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