An improved method for extrapolating worst-case Simulation Program with Integrated Circuit Emphasis (SPICE) model parameters for an integrated circuit including manufacturing semiconductor devices, measuring typical data and worst-case data with respect to various electrical characteristics of the manufactured devices, determining a set of typical SPICE model parameters using the typical data, and determining a set of worst-case SPICE model parameters using the typical data and the worst-case data. Determining the set of worst-case SPICE model parameters preferably includes extrapolating statistical model parameters using the typical data and the worst-case data and determining the set of worst-case SPICE model parameters using the statistical model parameters.