A needle-guide device, particularly for ultrasound probes, or the like, comprising a base body having means for connection to the probe and at least one elongated guide hole for receiving a needle-like surgical tool, characterized in that said needle-guide device, is made of at least two removably connectable parts, which are shaped in such a manner that each of them forms complementary parts of the peripheral delimiting wall of the elongated guide hole for the surgical tool which peripheral wall parts complete each other when said two parts, of the needle-guide device are connected, thereby forming an elongated guide hole for guiding the needle with a 360.degree. covering delimiting wall.