An image capturing device in which a plurality of pixels are two-dimensionally arrayed on one semiconductor substrate. First pixels are each provided with a first photoelectric conversion portion for capturing an image of a subject, the first amplifier portion is used for amplifying a signal generated at the first photoelectric conversion portion, and the first reset portion is used for resetting the signal generated at the first photoelectric conversion portion and a photoelectric conversion portion for photometry employed for photometering the subject. Second pixels are each provided with a second photoelectric conversion portion for capturing the image of the subject, the second amplifier portion is used for amplifying a signal generated by the second photoelectric conversion portion, and the second reset portion is used for resetting the signal generated at the second photoelectric conversion portion, The first pixels and the second pixels are arrayed with a specifically combined array pattern.

 
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> Detecting molecular binding by monitoring feedback controlled cantilever deflections

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