An effective vaccine for Marek's disease may be prepared using a viral
agent which is a Marek's disease virus unable to express a functional meq
protein. This viral agent is effective to elicit an immune response in a
chicken to very virulent strains of Marek's disease virus without causing
a significant degree of pathogenicity in the inoculated bird. Suitable
formulations of the vaccine for use in chickens include an effective
immunization dosage of this novel viral agent with a pharmaceutically
acceptable carrier or diluent.