The invention proposes a method of rejecting interference disturbing the reception by means of a reception system, of a signal emanating from a transmission system, the method comprising a calculation for weighting the signals Si(t), i varying from 1 to K, emanating from the reception system, based on the intercorrelation matrix RSS for the signals Si(t), the matrix RSS comprising on its diagonal the autocorrelation terms of the signals Si(t). The method is chiefly one wherein the weighting calculation comprises a step consisting in modifying the autocorrelation terms of the diagonal of the matrix RSS.