A vibration management system for a work machine may include at least one machine component configured to respond to input commands from an operator of the machine. One or more vibration sensors may be configured to output a signal indicative of a vibration level experienced by the operator. A controller may be configured to monitor the output signal from the one or more vibration sensors and determine an average vibration level experienced by the operator. The controller may also be configured to monitor the input commands from the operator and calculate a predicted response of the at least one machine component to at least one of the input commands. The controller may also be configured to determine a predicted vibration effect on the operator based on the predicted response and adjust an actual response of the at least one machine component to the at least one operator input command based on the predicted vibration effect and the average vibration level.