A coated preparation for the detection of a H. pylori infection according
to a urea breath test protocol which comprises a core composition
containing at least an isotope C-labeled urea, an excipient and a
lubricant in defined proportions and covered with 0.1.about.10 weight %
of a coating agent based on 100 weight % of the core composition. With
this preparation, the influence of the urease-producing bacteria resident
in organs other than the stomach, such as the mouth and throat, is
excluded to enable a diagnosis of H. pylori infection without the risk
for a false-positive test and with reasonable rapidity.