An isolated nucleic acid fragment encoding a chalcone synthase is disclosed. Construction of a recombinant DNA construct encoding all or a portion of the chalcone synthase, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels of the chalcone synthase in a transformed host cell are also discussed.

 
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> Diagnosis method of inflammatory, fibrotic or cancerous disease using biochemical markers

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