Devices and related methods are provided for irradiating a portion of a
body. A device according to one embodiment can include a radiation
needle, a fluorescent target, and an x-ray transmitting window. The
radiation needle can include a radiation conduit having a first and
second end for passing primary x-rays. An x-ray generator can generate
the primary x-rays and pass the primary x-rays from the first end to
second end. The fluorescent target can connect to the second end for
absorbing the primary x-rays and produce by fluorescence secondary x-rays
for irradiating a predetermined portion of the body. The fluorescent
target having a surface for absorbing the primary x-rays to fluoresce and
emit said secondary x-rays. The x-ray transmitting window can be
positioned adjacent to the fluorescent target such that the secondary
x-rays exit through the x-ray transmitting window. The secondary x-rays
can irradiate target tissue within the body.