Disclosed is an apparatus and method for controlling driving of an auxiliary device in a computer. The computer would include an operating system (OS) having at least one of a keyboard controller driver and a system BIOS that controls the enabled/disabled status of an internal auxiliary device based on the attachment status of an external auxiliary device. The internal auxiliary device may be a keyboard, a touch pad, or a pointing stick. The external auxiliary device may be a USB mouse. A method embodying the invention may include the steps of: periodically checking whether an external auxiliary device has been attached/detached to/from the computer, and disabling or enabling driving of the internal device or the external device depending on the checking results.