The present invention provides medicinal compositions characterized by comprising as the active ingredient either a compound represented by a formula [I] or a pharmaceutically acceptable composite thereof; ##STR00001## [wherein X represents oxygen or sulfur; R.sub.1 represents e.g., C.sub.1-4 alkyl, phenyl optionally substituted, etc.; Q.sub.1 represents spacer consisted of 0 to 3 carbon atoms; R.sub.2 represents, e.g., phenyl optionally substituted; R.sub.3 represents, e.g., hydrogen, C.sub.1-4 alkyl, or a group represented by the following formulae; --CONH--R.sub.6; R.sub.4 and R.sub.5 represent e.g., nitro, cyano, C.sub.1-4 alkylcarbonyl, respectively]; in particular, medicine which is useful as therapeutic and/or protective drugs for inflammatory diseases and/or allergic diseases by improving sick conditions accompanied with the stimulated phospholipase A(2) activity.