An interference-resistant wireless audio system includes a transceiver for transforming an audio signal into an RF signal, and a receiver for receiving RF signals in the air. The transceiver has an audio signal receiver, an audio data format converter, a frame and coding unit, a modulation module, an RF transceiver, a receiving/transmitting switch controller, an RF signal detector, and a channel switch controller electrically connected to the RF signal detector for controlling the RF transceiver to switch the used channel to another one after receiving a switch signal generated by the RF signal detector.