Communications are received from a user equipment UE on an uplink enhanced dedicated channel E-DCH. The radio resources of at least one downlink channel that supports the E-DCH are either released or configured or reconfigured while the E-DCH is maintained for the UE. The downlink channels may be E-AGCH, E-HICH, or E-RGCH, and the radio resources may include a temporary identifier E-RNTI, signature sequence, and/or channelization codes. At a serving cell change of the UE, either or both of the serving cell and the non-serving cell can add/configure/reconfigure a supporting downlink channel, all without terminating the E-DCH. The UE and the SRNC are notified by an E-RGCH release indicator whether the E-RGCH is released or not at a serving cell change, and the UE deletes its stored E-RGCH parameters when the release indicator indicates it is released.