Distal protection filter retrieval devices and methods of retrieving a distal protection filter. A filter retrieval catheter may comprise an inner tube, an outer tube disposed over the inner tube, an annular lumen disposed between the inner tube and the outer tube, and a tapered member coupled to the lumen. The tapered member may be movable between a first position for passing a lesion and a second position retrieving a filter.

 
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> Human E3.alpha. ubiquitin ligase family

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