The present invention relates to prognostic methods which are useful in
medicine, particularly cancer chemotherapy. The object of the invention
to provide a method for assessing GST-pi expression levels in fixed or
fixed and paraffin embedded tissues and prognosticate the probable
resistance or sensitivity of a patient's tumor to treatment with
platinum-based therapies by examination of the amount of GST-pi mRNA in a
patient's tumor cells and comparing it to a predetermined threshold
expression level. More specifically, the invention provides to
oligonucleotide primer pair GST-piand methods comprising their use for
detecting levels of GST-pi mRNA.