A multi-purpose toothbrush for promoting oral hygiene includes an elongated shaft having a brushing section that includes a plurality of bristles extending radially outwardly therefrom. The brushing section is coated with a predetermined quantity of a tooth-cleaning agent that is activatable via water. The shaft further includes an accessory dispensing section integral with a gripping section and oppositely spaced from the brushing section for providing dental floss and mouthwash. A plurality of protective wrappers are removably positioned about the toothbrush for maintaining same in a substantially sanitary condition during non-use conditions.