An endoscopic retractor instrument assembly includes a balloon having a pair of expandable or inflatable end portions and at least one expandable or inflatable spacer portion connecting the end portions to one another. A fastener is provided for securing the balloon to a distal end of an endoscopic insertion member, with the balloon being disposed in a collapsed configuration along an outer surface of the endoscopic insertion member. An inflation element is operatively coupled with the balloon for enabling an inflating of the balloon from the collapsed configuration to an expanded use configuration in which the spacer portion pushes the end portions apart from one another and in which the balloon extends at least partially in a distal direction away from the distal end of the endoscopic insertion member for spreading internal tissues of a patient to facilitate access to the tissues via the endoscopic insertion member.