Novel nucleic acid sequences encoding hemipteran muscarinic receptors, and recombinant expressions and host cells comprising the same are disclosed. Isolated hemipteran muscarinic receptors, host cells expressing hemipteran muscarinic receptors, methods of producing the hemipteran muscarinic receptors and antibodies specific for hemipteran muscarinic receptors are also disclosed. Methods of identifying modulators of hemipterana muscarinic receptors are disclosed.