The compositions relate to retroviral vectors encoding intein containing polypeptides which, when expressed in an eukaryotic cell, are capable of generating cyclic peptides. The retroviral vectors are used in methods for producing cyclic peptides and for identifying peptides capable of altering cellular phenotypes.

 
Web www.patentalert.com

< Transgenic Drosophila having a disrupted Parkin gene and exhibits reduced climbing ability

< Screening assays for agonists and antagonists of the hedgehog signaling pathway

> Multipotent neural stem cell cDNA libraries

> Prevention of loss and restoration of bone mass by certain prostaglandin agonists

~ 00287