A tire assembly with integrated electronic components includes a tire structure and an integrated electronics assembly, which preferably includes at least a radio frequency (RF) device and a multi-frequency antenna that enables wireless communication in at least first and second resonant frequency bands. Such multi-frequency antenna further comprises at least first and second antenna wires connected to the RF device, thus facilitating the transmission of RF signals which may include information such as tire identification information or measured condition information such as tire temperature, pressure, and other characteristics. The first and second antenna wires preferably function together as at least two dipole antennas, for example, two half-wave dipole antennas, or one half-wave dipole antenna and one three-half-wave dipole antenna. A two-wire configuration may be more readily implemented and also designed to reduce strains concentrated at the connection point(s) between the RF device and the antenna wires.