A system, method, and apparatus are provided for selectively isolating particular ICs on an I.sup.2C bus system. Selective isolation of particular ICs allows the particular isolated ICs to communicate with each other and/or with other components at a data transfer rate that is greater than the data transfer rate for the I.sup.2C bus system. A switch is operative in one mode to selectively isolate an auxiliary or separate I.sup.2C portion containing the ICs to be isolated and operative in another mode to allow the auxiliary I.sup.2C portion to be part of the main I.sup.2C bus sys portion tem. Proper pull-up resistors associated with the switch aid in allowing a faster data transfer rate by speed up of the low to high transition for operation of the isolated ICs.