A particle size (or particle diameter) variable reactor comprises a granular substrate and a capturing unit fixed onto the surface of the granular substrate. The capturing unit comprises a rod-shaped body having a length of 810 nm or less, a configuration variable element which may be structurally transformed when stimulation is applied, and a capturing structured body which specifically captures an object to be captured. The particle size variable reactor is highly biodegradable and environmentally friendly, and can specifically act on and thus selectively capture its target alone. The reactor may preferably be used in various fields including medical and industrial fields.

 
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