Nucleic acid molecules encoding full length PTP20, PCP-2, BDP1, mCLK2,
mCLK3, mCLK4, and SIRP polypeptides, portions of such nucleic acid
molecules, nucleic acid vectors containing such nucleic acid molecules,
recombinant cells containing such nucleic acid vectors, polypeptides
purified from such recombinant cells, antibodies to such polypeptides,
and methods of identifying compounds that bind such polypeptides or
abrogate their interactions with natural binding partners. Methods for
diagnosing abnormal conditions in an organism with PTP20, PCP-2, BDP1,
mCLK2, mCLK3, mCLK4, and SIRP related molecules or compounds. PTP20,
PCP-2, BDP1, mCLK2, mCLK3, mCLK4, or SIRP polypeptides, nucleic acids
encoding such polypeptides, cells, tissues and animals containing such
nucleic acids, antibodies to such polypeptides, assays utilizing such
polypeptides, and methods relating to all of the foregoing. Methods for
treatment, diagnosis, and screening are provided for diseases related to
PTP20, PCP-2, BDP1, mCLK2, mCLK3, mCLK4, and SIRP polypeptide or
conditions characterized by an abnormal interaction between such a
polypeptide and its binding partner.