The invention relates to compounds and methods for inhibiting human platelet aggregation, thrombosis and cell activation mediated by PAR1 and PAR4 using peptide analogs of Arg-Pro-Pro-Gly-Phe that contain one or more amino acid substitutions. The invention also includes screening methods for identifying compounds that inhibit thrombin mediated activities.

 
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< Guanosine triphosphate (GTP) binding protein-coupled receptor proteins

< Histogranin-like peptides, processes for their preparation and uses thereof

> Pretargeting methods and compounds

> Ex vivo remodeling of excised blood vessels for vascular grafts
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