Disclosed is a bone fracture fixation system, such as for reducing and compressing fractures in the proximal femur. The fixation system includes a plurality of elongated bodies with a helical cancellous bone anchor on a distal end of each of the bodies. An axially moveable plate with a plurality of openings is carried by the proximal end of the elongated bodies. The elongated bodies are rotated into position across the fracture or separation between adjacent bones and into the adjacent bone or bone fragment, and the plate is distally advanced to apply secondary compression and lock the device into place. The device may also be used for soft tissue attachments.