The present invention relates to a compound of formula (I) in which
R.sup.1 and R.sup.2 independently represent phenyl, thienyl or pyridyl
each of which is optionally substituted by one, two or three groups
represented by Z; and R.sup.3 is H, a C.sub.1-3alkyl group, a
C.sub.1-3alkoxymethyl group, trifluoromethyl, a hydroxyC.sub.1-3alkyl
group, an aminoC.sub.1-3alkyl group, C.sub.1-3alkoxycarbonyl, carboxy,
cyano, carbamoyl, mono or di C.sub.1-3alkylcarbamoyl, acetyl, or
hydrazinocarbonyl of formula --CONHNR.sup.aR.sup.b wherein R.sup.a and
R.sup.b are as defined for R.sup.4 and R.sup.5 respectively; X is CO or
SO.sub.2; Y is absent or represents NH optionally substituted by a
C.sub.1-3alkyl group; R.sup.4 and R.sup.5 independently represent: a
C.sub.1-6alkyl group; an (amino)C.sub.1-4alkyl-group in which the amino
is optionally substituted by one or more C.sub.1-3alkyl groups; an
optionally substituted non-aromatic C.sub.3-15carbocyclic group; a
(C.sub.3-12cycloalkyl)C.sub.1-3alkyl-group; a group
--(CH.sub.2).sub.r(phenyl).sub.s; naphthyl; anthracenyl; a saturated 5 to
8 membered heterocyclic group containing one nitrogen and optionally one
of the following: oxygen, sulphur or an additional nitrogen wherein the
heterocyclic group is optionally substituted; 1-adamantylmethyl; a group
--(CH.sub.2).sub.t Het where Het represents an aromatic heterocycle
optionally substituted; or R.sup.4 represents H and R.sup.5 is as defined
above; or R.sup.4 and R.sup.5 together with the nitrogen atom to which
they are attached represent a saturated 5 to 8 membered heterocyclic
group; R.sup.6 is H, a C.sub.1-3alkyl group, a C.sub.1-3alkoxymethyl
group, trifluoromethyl, a hydroxyC.sub.1-3alkyl group,
C.sub.1-3alkoxycarbonyl, carboxy, cyano, carbamoyl, mono or di
C.sub.1-3alkylcarbamoyl, acetyl, or hydrazinocarbonyl of formula
--CONHNR.sup.aR.sup.b; with provisos; to processes for preparing such
compounds, to their use in the treatment of obesity, psychiatric and
neurological disorders particularly obesity, to methods for their
therapeutic use and to pharmaceutical compositions containing them.
