The invention provides twenty-one butyrylcholinesterase variants having increased cocaine hydrolysis activity as well as the corresponding encoding nucleic acids. The invention further provides methods of hydrolyzing a cocaine-based butyrylcholinesterase substrate as well as methods of treating a cocaine-induced condition.

 
Web www.patentalert.com

< Detecting and treating reproductive tract disorders

< Mutant possessing uracil phosphoribosyl transferase activity

> C-nitroso compounds and use thereof

> Use for deferiprone

~ 00264