According to the invention, there is provided a novel soybean variety designated XB18C06. This invention thus relates to the seeds of soybean variety XB18C06, to the plants of soybean XB18C06 to plant parts of soybean variety XB18C06 and to methods for producing a soybean plant produced by crossing plants of the soybean variety XB18C06 with another soybean plant, using XB18C06 as either the male or the female parent.