A gene for type C Niemann-Pick disease (NP-C) is disclosed, along with the amino acid sequence of the encoded peptide. Applications which are made possible by the present invention include detection of NP-C carriers and diagnosis of NP-C sufferers. The murine ortholog of the human gene is also disclosed.

 
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< Nucleic acids encoding JTT-1 protein

< Diagnostic neodymium(III), ytterbium(III), or erbium(III) ion-ligand complexes

> Polyketides and antibiotics

> Transgenic plants

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