A wireless communication device (100) employs a method and apparatus for automatically initiating a communication with a target device. The communication device includes, inter alia, a user interface (115), an acoustic transducer (113), and an acoustic receptor (109). The user interface receives an identification of the target device (e.g., a telephone number) from a user while the communication device is configured in a first physical or mechanical configuration of at least two user-selectable configurations. Responsive to detecting a reconfiguration of the communication device from the first configuration (e.g., closed) into a second configuration (e.g., open), the communication device automatically initiates the communication with the target device, thereby eliminating the need for manual call initiation after the communication device is properly positioned for in-call use.