The present invention provides compositions of matter, kits and methods for their use in the treatment of MAP kinase-related conditions and/or HMG-CoA reductase-related conditions. In particular, the invention provides compositions for treating inflammatory and/or cardiovascular conditions in an animal subject by inhibiting p38.alpha. MAP kinase and/or HMG-CoA reductase, as well as providing formulations and modes of administering such compositions. The invention further provides methods for the rational design of inhibitors of MAP kinase, HMG-CoA reductase, or both for use in the practice of the present invention.

 
Web www.patentalert.com

< Ophthalmological use of roflumilast for the treatment of diseases of the eye

< Isoxazole derivatives

> Methods and compositions for enhancing degradation of nuclear receptor transcription factors and uses thereof

> Albumin fusion proteins

~ 00255