The present invention discloses compounds of formula I
##STR1##
wherein Ar, Z, m, n, p, R1 and R8 are herein defined,
said compounds being novel antagonists for melanin-concentrating hormone (MCH),
as well as methods for preparing such compounds. In another embodiment, the invention
discloses pharmaceutical compositions comprising such MCH antagonists as well as
methods of using them to treat obesity, metabolic disorders, eating disorders such
as hyperphagia, and diabetes.
