The present invention relates to using a compound having the formula (I) wherein T is I) thienyl, which optionally is substituted with halogen, or II) phenyl optionally substituted with halogen and/or C_1-6-alkyl; E is a bond, —CH₂— or —CO—; L is a bond, —CH₂—, —CHR⁴— or —NR³—; R³ is H, C_1-6-alkyl, C_1-6-acyl or —COR⁴; R⁴ is morpholino or C_1-6-amido; R⁶ and R⁷ are independently hydrogen or C_1-6-alkyl; and R⁸ and R⁹ are independently hydrogen or C_1-6-alkyl, as well as pharmaceutically acceptable salts, hydrates and solvates thereof, in the manufacture of a medicament for the treatment or prevention of diabetes, syndrome X, obesity, glaucoma, hyperlipidemia, hyperglycemia, hyperinsulinemia, osteoporosis, tuberculosis, dementia, depression, virus diseases and inflammatory disorders. ##STR1##