A mammalian D2 dopamine receptor gene has been cloned. Thus, DNA sequences
encoding all or a part of the dopamine receptor are provided, as well as the corresponding
polypeptide sequences and methods for producing the same both synthetically and
via expression of a corresponding sequence from a host transformed with a suitable
vector carrying the corresponding DNA sequence. The various structural information
provided by this invention enables the preparation of labeled or unlabeled immunospecific
species, particularly antibodies, as well as nucleic acid probes labeled in conventional
fashion. Pharmaceutical compositions and methods of using various products of this
invention are also provided.