The present invention presents a pharmaceutical composition for oral use with
improved absorption, which comprises drug, aminoalkyl methacrylate copolymer E,
and acidic substance and is obtained by bringing said 3 components together and
uniformly mixing at least this polymer and this acidic substance, and a method
of improving oral absorption by using this pharmaceutical composition. Moreover,
the present invention presents an agent for improving oral absorption that increases
drug permeability of the digestive tract mucous membrane and/or mucous layer present
on the surface of this membrane, whose active ingredient is aminoalkyl methacrylate
copolymer E. In addition, the present invention presents an oral agent for improving
absorption by increasing drug permeability of the digestive tract mucous membrane
and/or the mucous layer distributed over this mucous membrane, whose effective
component is aminoalkyl methacrylate copolymer E.