A treatment system and method for enhancing absorption of substances provided on a surface of a patient's skin, includes applying a substance to the surface of the patient's skin by way of a probe that provides at least one of: i) electrical pulses to the skin surface, and ii) vibrational pulses to the skin surface, in order to cause absorption of the substance within the patient's skin. At the same that the substance is applied to the skin, a gauze pad is provided between the probe and the patient's skin. The gauze pad allows for the probe to be moved over the surface of the patient's skin with less friction than if no gauze pad is used, in order to obtain easier movement of the probe with respect to the skin, and to obtain a more even application of the substance to the skin.