An electromagnetic immune tissue invasive system includes a primary device housing. The primary device housing having a control circuit therein. A shielding is formed around the primary device housing to shield the primary device housing and any circuits therein from electromagnetic interference. A lead system transmits and receives signals between the primary device housing. The lead system is either a fiber optic system or an electrically shielded electrical lead system.

 
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> Methods for treating neuropathological states and neurogenic inflammatory states and methods for identifying compounds useful therein

> VGF fusion polypeptides

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