The present invention features compounds useful for inhibiting RNase P activity.
These compounds can be used as therapeutics for treating or preventing a variety
of bacterial infections. The compounds belong to several classes including mono-
and bis-guanylhydrazones, guanylhydrazone mimetics, and benzothiazolium compounds.
Exemplary compounds are compounds of formula I:
Y—(NR)k—U1—(NR")I—A—(NR1)m—U2—(NR2)n—Z I
with substituents as described herein.