A method, system and program product for providing domain level business object keys in Enterprise JavaBeans (EJB) applications. An instance of an EntityBean object is provided with both a primary key and a domain key class. The primary key class is associated with a home selected for the EntityBean object, and the domain key class is associated with a particular business application within which the EntityBean object is being utilized. The EntityBean and associated home is utilized across different business applications, while ensuring uniqueness across the different applications. Also, a common interface for the primary key is introduced that has methods, which (1) provide an initialized instance of associated domain key classes from a concrete primary key subclass, wherein a concrete primary key subclass knows its associated domain key and is able to initialize the domain key from a subset of attributes of the primary key, and (2) creates an initialized instance of a primary key subclass from a given domain key and a context object.