A system is provided for testing a flexible tube. First and second hollow mandrels are inserted into opposing ends of the tube. Each mandrel has a conically tapered portion at one end thereof and a cylindrical portion extending from the conically tapered portion. The cylindrical portion has a plurality of annular indentations formed thereabout. Each of a plurality of clamps encircle the tube in line with one annular indentation to sealably engage the tube. A fluid delivery system is coupled between the cylindrical portions of the mandrels to deliver a flow of fluid through the tube via the mandrels. A measured strain producing load, continuous or cyclical, is applied by an apparatus which controllably moves the first mandrel relative to the second mandrel such that a cross-sectional shape of the tube between the mandrels is altered.