A multilayered material is provided that exhibits therapeutic effects for relieving the pain and swelling of various forms of arthritis (particularly osteoarthritis), delaying the onset of osteoarthritis, or preventing hypothermia or alleviating conditions caused by hypothermia. The flexible, breathable multilayered material includes a first layer of soft and hypoallergenic material (e.g., cotton, silk, linen), a second layer of soft, heat retentive material (e.g., wool, cashmere) contacting the first layer, and a third layer of water repellent material contacting the second layer. Additionally, the multilayered material provides a thin, flexible, breathable fabric that can be used to construct various garments, devices, and gears to combat harsh weather conditions.