The present invention relates to novel hydroxyethylene compounds having Asp2 (-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated -amyloid levels or -amyloid deposits, particularly Alzheimer's disease.

 
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> Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor

> Pharmaceutical preparation comprising vWF propeptide

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