A system and method for providing optimum wireless communication spreading code selection such that communication channel interpath interference is minimized. In Direct-Sequence Spread-Spectrum, the autocorrelation properties of a spreading code greatly affects the inherent ability of a system to resist multipath. Low/spreading gain codes (or "short" codes) associated with high data rates do not perform well where large-amplitude multipath is present. The system and method presented herein overcomes this problem by selecting spreading codes in such a way that interference caused by multipath is minimized. The system and method does so by determining the characteristics of the radio-frequency link in order to select a spreading code that will minimize interpath interference.