The methods of the invention provide a means for rapid analysis of gene function in a variety of systems. The invention allows screening of large libraries of nucleotide sequences for involvement in physiological pathways of interest. The methods of the invention also provide an efficient means of identifying and isolating nucleotide sequences that modulate a physiological pathway of interest from a population of nucleotide sequences.

 
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> Osteoblast factor(s) that regulates human prostate cancer migration to and invasion of bone

> Method of improving efficacy of biological response-modifying proteins and the exemplary muteins
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