The invention describes syntheses and purifications of several perfluorocarbon-soluble compounds having a general formula R.sub.F-L-X or R.sub.F-L-X-L-R.sub.F, wherein R.sub.F is a perfluorocarbon group, X is a hydrophilic moiety, and L is an amide linkage of general structure --CO--NH--. The invention also provides microemulsions comprising a PFC forming an oil phase, water or aqueous solution forming a water phase, and a PEG-based fluorosurfactant with an HFB (hydrophilic groups to fluorophilic groups balance) value from about 7 to about 13. The invention also provides a method of amidification of a fluorocompound. The method involves mixing perfluoroacid chloride of a general formula C.sub.nF.sub.2n+1COCl with a compound containing an amine group with a general structure R--NH.sub.2 under reaction conditions sufficient to obtain a product having a general formula C.sub.nF.sub.2n+1--CONH--R.