The catalytic hydrogenation of HBA and/or HMPA is improved by either or both of (1) increasing the temperature in the hydrogenation zone from about 50 to 70 C. at the inlet to above 80 C. at the outlet and (2) raising the pH of the hydrogenation feed to 4.5-6.0 before hydrogenation.

 
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> Dehydrogenase and a gene encoding the same

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