The present invention relates to an isothiazole derivative of the following formula 1 or nontoxic salt thereof: ##STR1##

    • wherein, R1 is hydrogen, alkoxy group or halogen group; R2 is methyl or amino group.
  • According to the present invention, isothiazole derivative or nontoxic salt thereof having antipyretic, analgesic and antiphlogistic activity and an improved side effect; process for the preparation thereof; and pharmaceutical composition including the same can be provided.

     
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